FloM-PET

The FloM-pet is an instrument to measure blood flow in the eye on the rat. The instrument is mounted on a dedicated support. The measuring device rotate around the pupil of the animal’s eye so that any point inside the funds can be reached without readjusting the entrance pupil. Fundus and probing beam can be visualised.



Specifications :

Instrument

  • Size: 13 cm x 8.5 cm x 3.5 cm
  • weight: less than 300g
  • Power consumption with the automated acquisition device : 5.7 W
  • A gel must be used between the eye of the rat and the instrument in order

Probing light

  • Wavelength: 780 nm
  • Intensity: 250 μW
  • Beam diameter at the pupil : 1.5 mm

Optical principle

  • Confocal (self-aligned)

Fundus illumination

  • provided through 6 LED @ 540 +/- 30 nm
  • inner pupil diameter: 2.6 mm
  • outer pupil diameter: 4.3 mm

Data Analysis

  • The instrument delivers an electrical signal, which is analysed by dedicated FloM-acquisition.

References

  • M. Mentek, F. Truffer, C. Chiquet, D. Godin-Ribuot, S. Amoos, C. Loeuillet, M. Bernabei, and M. Geiser, “Compact Laser Doppler Flowmeter (LDF) Fundus Camera for the Assessment of Retinal Blood Perfusion in Small Animals.,” PLoS ONE, vol. 10, no. 7, p. e0134378, 2015.